Comparing of Cu/Zn SOD Gene Expression of Lymphocyte Cell and Malondialdehyde Level in Active Men and Women after Physical Training

AuthorBakhtiar Tartibianen
AuthorBehrouz Baghaieeen
AuthorBehzad Baradaranen
AuthorMohammadreza Aliparastyen
AuthorShohreh Almasyen
Issued Date2012-09-30en
AbstractBackground: The purpose of this study is to compare Cu/Zn SOD mRNA and MDA level as a result of a session incremental exercise in active women and men. Materials and Methods : This research is a quasi-experimental study with repeated measurements in which 14 active female and 13 male subjects with age range 22-24 participated voluntarily. Then, blood was taken from brachial vein of the subjects in three stages before and after GXT (Graded exercise test) and 3 hours after that and SYBER Green PCR Master mix reagent Kit and Real time-PCR were used to measure Cu/Zn SOD mRNA and spectrophotometer was used to measure MDA level.Results: MDA levels increased significantly in men during the recovery stage and after the exercise (p1=0.012 and p2 =0.014), but it did not increase significantly in active women. Also, MDA difference between the two genders was not reported significant in any of the exercise stages. Cu/Zn SOD gene expression did not increase significantly in either sex.Conclusion: The risk of injury from free radicals is more probable in active men than active women and vigorous physical activity does not significantly increase the Cu/Zn SOD gene expression. en
DOIhttps://doi.org/en
KeywordGene expressionen
KeywordSuper oxidase dismutaseen
KeywordOxidative stressen
KeywordActive peopleen
PublisherBrieflandsen
TitleComparing of Cu/Zn SOD Gene Expression of Lymphocyte Cell and Malondialdehyde Level in Active Men and Women after Physical Trainingen
TypeResearch Articleen

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