Assessing Absorption Coefficient of Hemoglobin in the Breast Phantom Using Near-Infrared Spectroscopy
| Author | Parinaz Mehnati | en |
| Author | Maede Jafari Tirtash | en |
| Author | Mohammad Sadegh Zakerhamidi | en |
| Author | Parisa Mehnati | en |
| Issued Date | 2016-10-01 | en |
| Abstract | Background: Blood concentrations and oxygen saturation levels are important biomarkers for breast cancer diagnosis. Objectives: In this study, the absorption coefficient of hemoglobin (Hb) was used to distinguish between normal and abnormal breast tissue. Materials and Methods: A near-infrared source (637 nm) was transmitted from major and minor vessels of a breast phantom containing 2×, 4× concentrations of oxy- and deoxy-Hb. The absorption coefficients were determined from spectrometer (SM) and powermeter (PM) data. Results: The absorption coefficients were 0.075 ± 0.026 cm-1 for oxygenated Hb (normal) in major vessels and 0.141 ± 0.023 cm-1 at 4× concentration (abnormal) with SM, whereas the breast absorption coefficients were 0.099 ± 0.017 cm-1 for oxygenated Hb (normal) in minor vessels and 0.171 ± 0.005 cm-1 at 4× concentrations with SM. A comparison of the data obtained using a SM and a PM was not significant statistically. Conclusion: The study of the absorption coefficient data of different concentrations of Hb in normal and abnormal breasts via the diffusion of near-infrared light is a valuable method and has the potential to aid in early detection of breast abnormalities with SM and PM in major and minor vessels. | en |
| DOI | https://doi.org/10.5812/iranjradiol.31581 | en |
| Keyword | Hemoglobin | en |
| Keyword | Optical Properties | en |
| Keyword | Near Infrared Spectroscopy | en |
| Keyword | Absorption Coefficient | en |
| Publisher | Brieflands | en |
| Title | Assessing Absorption Coefficient of Hemoglobin in the Breast Phantom Using Near-Infrared Spectroscopy | en |
| Type | Research Article | en |