Effects of Variations of Flow and Heart Rate on Intra-Aneurysmal Hemodynamics in a Ruptured Internal Carotid Artery Aneurysm During Exercise
| Author | Ali Sarrami-Foroushani | en |
| Author | Mohsen Nasr Esfahany | en |
| Author | Hamidreza Saligheh Rad | en |
| Author | Kavous Firouznia | en |
| Author | Madjid Shakiba | en |
| Author | Hossein Ghanaati | en |
| Issued Date | 2016-01-01 | en |
| Abstract | Background: Hemodynamics is thought to play an important role in the mechanisms responsible for initiation, growth, and rupture of intracranial aneurysms. Computational fluid dynamic (CFD) analysis is used to assess intra-aneurysmal hemodynamics. Objectives: This study aimed to investigate the effects of variations in heart rate and internal carotid artery (ICA) flow rate on intra-aneurysmal hemodynamics, in an ICA aneurysm, by using computational fluid dynamics. Patients and Methods: Computed tomography angiography (CTA) was performed in a 55 years old female case, with a saccular ICA aneurysm, to create a patient-specific geometrical anatomic model of the aneurysm. The intra-aneurysmal hemodynamic environments for three states with different flow and heart rates were analyzed using patient-specific image-based CFD modeling. Results: Results showed significant changes for the three simulated states. For a proportion of the states examined, results were counterintuitive. Systolic and time-averaged wall shear stress and pressure on the aneurysm wall showed a proportional evolution with the mainstream flow rate. Conclusion: Results reinforced the pivotal role of vascular geometry, with respect to hemodynamics, together with the importance of performing patient-specific CFD analyses, through which the effect of different blood flow conditions on the aneurysm hemodynamics could be evaluated. | en |
| DOI | https://doi.org/10.5812/iranjradiol.18217 | en |
| Keyword | Fluid Dynamics | en |
| Keyword | Internal Carotid Artery | en |
| Keyword | Aneurysm | en |
| Keyword | Heart Rate | en |
| Publisher | Brieflands | en |
| Title | Effects of Variations of Flow and Heart Rate on Intra-Aneurysmal Hemodynamics in a Ruptured Internal Carotid Artery Aneurysm During Exercise | en |
| Type | Research Article | en |