Could molecular studies save Hydroxyethyl starch from total disappearance?

AuthorParisa Sezarien
AuthorKamran Mottaghien
AuthorMasoud Nashibien
AuthorFarhad Safarien
OrcidParisa Sezari [0000-0003-3874-1050]en
OrcidMasoud Nashibi [0000-0003-3825-9889]en
OrcidFarhad Safari [0000-0002-1479-8477]en
Issued Date2018-12-31en
AbstractUp until now, hydroxyethyl starch (HES) solutions have mainly been indicated as "volume expanders". Recent unfavorable reports of these solutions such as probability of kidney injury or inducing coagulopathy have relatively ejected these solutions in many centers, particularly in European countries. Despite several confirming studies, multiple anecdotal letters or reviews has challenged total disappearance of these colloids from medicine practice. Also, some novel observations emphasized the distinguished ability of HES to preserve the microvascular integrity even at the presence of an inflammatory process. Despite extreme statements has been published demanding immediate suspension of these fluids from the market, it seems logical to revise the most recent studies which may declare new pathways to approach HES family of solutions.?en
DOIhttps://doi.org/10.22037/jcma.v3i4.24282en
KeywordColloiden
KeywordHydroxyethyl starchen
Keywordfluid resuscitationen
KeywordHESen
KeywordGlycocalyxen
Keyworden
PublisherBrieflandsen
TitleCould molecular studies save Hydroxyethyl starch from total disappearance?en
TypeReviewen

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