Lack of association between Interleukin-12 gene polymorphism (rs568408 G/A) and susceptibility to chronic hepatitis B virus infection
| Author | Seddigheh Heidarian | en |
| Author | Farzaneh Sabahi | en |
| Author | Seyed Reza Mohebbi | en |
| Author | Mohammad Reza Zali | en |
| Issued Date | 2016-06-20 | en |
| Abstract | Introduction: Hepatitis B is a potentially life-threatening infection that causes acute infection and chronic hepatitis with progression to cirrhosis and hepatocellular carcinoma (HCC). Interleukin-12 (IL12) is responsible for activation of Th1 immune responses, leading to possible clearance of HBV infection from the host’s body. The host’s immune-genetic background plays an important role in the pathogenesis of infectious diseases. The aim of the present study was to investigate the association of interleukin 12A single nucleotide polymorphism (rs568408 G/A) with chronic HBV infection. | en |
| DOI | https://doi.org/10.22110/jkums.v20i1.2685 | en |
| Keyword | Chronic hepatitis B infection | en |
| Keyword | single nucleotide polymorphisms | en |
| Keyword | Interleukin 12 | en |
| Keyword | Iran | en |
| Publisher | Brieflands | en |
| Title | Lack of association between Interleukin-12 gene polymorphism (rs568408 G/A) and susceptibility to chronic hepatitis B virus infection | en |
| Type | Research Article | en |
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