Effectiveness of Twin-Beam Dual-Energy Computed Tomography in Characterization of Solitary Pulmonary Nodules Larger Than 5 mm

AuthorSaim Turkogluen
AuthorMesut Özgökçeen
OrcidSaim Turkoglu [0000-0001-8247-2009]en
OrcidMesut Özgökçe [0000-0002-3095-2446]en
Issued Date2024-07-31en
AbstractBackground: Advancements in technology have significantly improved the diagnosis of solitary pulmonary nodules in the lungs. Various computed tomography (CT) imaging techniques, including modern dual-energy computed tomography (DECT), have enhanced the ability to accurately classify pulmonary nodules as benign or malignant. In this study, three different dual-energy parameters — iodine load, contrast load, and visual assessment — were evaluated for their potential in characterizing pulmonary nodules. Objectives: The aim of this study was to assess the reliability and effectiveness of DECT in distinguishing benign from malignant pulmonary nodules using different parameters, including visual assessment, iodine concentration, and contrast load. Patients and Methods: This prospective study included patients who underwent contrast-enhanced thoracic DECT for solitary pulmonary nodules, had histopathological examination results, or had at least a two-year follow-up CT scan. Patients with nodules smaller than 6 mm or completely calcified nodules were excluded. Patients diagnosed with a suspicious solitary pulmonary nodule on chest radiography and subsequently underwent contrast-enhanced DECT, or those diagnosed with a lung nodule on routine non-contrast CT scans and later evaluated using DECT, were included in the study. Results: A total of 59 patients [30 males (50.8%) and 29 females (49.2%)] with a solitary pulmonary nodule met the inclusion criteria. Among the 59 pulmonary nodules, 16 (27.1%) were malignant, and 43 (72.9%) were benign. Of the benign lesions, 23 (53.5%) were found in males and 20 (46.5%) in females. Conclusion: Dual-energy computed tomography provides valuable contributions in differentiating benign and malignant pulmonary nodules. In this study, the diagnostic value of three different approaches — visual iodine coverage color map, iodine concentration, and contrast load — was demonstrated in distinguishing these lesions.en
DOIhttps://doi.org/10.5812/iranjradiol-149360en
URIhttps://brieflands.com/journals/ijradiology/articles/149360en
KeywordDual Energyen
KeywordBenignen
KeywordMalignanten
KeywordPulmonary Noduleen
KeywordTwin-Beamen
KeywordIodine Mapen
KeywordContrast Loaden
KeywordIodine Loaden
PublisherBrieflandsen
TitleEffectiveness of Twin-Beam Dual-Energy Computed Tomography in Characterization of Solitary Pulmonary Nodules Larger Than 5 mmen
TypeResearch Articleen

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