The Effect of OnabotulinumtoxinA on the Symptoms and Quality of Life in Women with Urge Urinary Incontinence
| Author | Firoozeh Veisi | en |
| Author | Hossein Abdi | en |
| Author | Masoumeh Bayati | en |
| Orcid | Firoozeh Veisi [0000-0002-6699-9430] | en |
| Orcid | Hossein Abdi [0000-0003-4292-3199] | en |
| Orcid | Masoumeh Bayati [0000-0001-9484-2740] | en |
| Issued Date | 2021-12-31 | en |
| Abstract | Objectives: To determine the effect of OnabotulinumtoxinA intradetrusor injection on quality of life (QOL) and symptoms of women with urge urinary incontinence. Methods: Twenty five postmenopausal patients with urge urinary incontinence, underwent cystoscopy and 200 U OnabotulinumtoxinA intradetrusor injections (0.5 cc at each injection). The effects of botox have been evaluated on urge urinary incontinence and quality of life. Results: The mean urge urinary incontinence per day was 7.25 which decreased to 2.87 (month 1) and 3.12 (month 6); P value = 0.019. The mean of nocturnal episodes was 3 which decreased to 0 and 1in the first and sixth months, respectively (P = 0.007). Baseline mean I-QOL total score was 43.37 which reached 82.12 (month 1) and 78.87 (month 6); P < 0.001. Conclusions: OnabotulinumtoxinA significantly decreased urinary urge incontinence and nocturia at month 1 and 6. The quality of life of patients has improved. | en |
| DOI | https://doi.org/10.5812/jcrps.111274 | en |
| Keyword | Urge Urinary Incontinence | en |
| Keyword | Overactive Bladder | en |
| Keyword | Neurogenic Detrusor Overactivity | en |
| Keyword | OnabotulinumtoxinA | en |
| Publisher | Brieflands | en |
| Title | The Effect of OnabotulinumtoxinA on the Symptoms and Quality of Life in Women with Urge Urinary Incontinence | en |
| Type | Research Article | en |
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