The Effects of Prolotherapy With Hypertonic Dextrose Versus Prolozone (Intraarticular Ozone) in Patients With Knee Osteoarthritis

AuthorMasoud Hashemien
AuthorParviz Jalilien
AuthorShirin Mennatien
AuthorAlireza Kooshaen
AuthorRamin Rohanifaren
AuthorFirouz Madadien
AuthorSeyed Sajad Razavien
AuthorFarinaz Taherien
Issued Date2015-10-01en
AbstractBackground: Knee osteoarthritis (KOA) is a common disabling disease. Limited studies have demonstrated that prolotherapy with dextrose or with prolozone can be helpful in the treatment of patients with KOA. Objectives: In the current study, we compared the results between these two treatment methods. Patients and Methods: In the current randomized clinical trial, 80 patients with mild to moderate KOA were randomly assigned equally into two groups (ozone group and dextrose group). In each group, injections were repeated three times with 10-day intervals. Before the treatment and 3 months after the injections, the pain intensity was measured by using a visual analogue scale and the Western Ontario and McMaster university arthritis index scores. Finally, the results were compared between the two groups. Results: In the two groups, the pain intensity and WOMAC scores significantly decreased and increased, respectively (P < 0.001). However, there was no significant difference between the two groups. Conclusions: Prolotherapy with dextrose and with prolozone result in the same pain relief or functional improvement in patients with mild to moderate KOA.en
DOIhttps://doi.org/10.5812/aapm.27585en
URIhttps://brieflands.com/journals/aapm/articles/17496en
KeywordOsteoarthritisen
KeywordKneeen
KeywordProlotherapyen
KeywordProlozoneen
KeywordDextroseen
PublisherBrieflandsen
TitleThe Effects of Prolotherapy With Hypertonic Dextrose Versus Prolozone (Intraarticular Ozone) in Patients With Knee Osteoarthritisen
TypeResearch Articleen

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