Impact of disability and depression on quality of life in individuals with multiple sclerosis

Abstract

Background: Disability and depression are important predictors of reduced quality of life in individuals with Multiple Sclerosis (MS) . Objective : This study was performed to assess the effect of disability and depression on the quality of life individuals with MS. Methods: This was a comparative study, performed on 53 individuals with MS and a group of healthy individuals following age and sex adjustment in the city of Qazvin in 2009. These people were compared using the quality of life questionnaire (SF-36 ( , Expanded Disability Status Scale (EDSS), and the Beck Depression Inventory. Data were analyzed using t-test, linear regression and multivariate analysis. Findings: Patients with MS had lower scores compared to the general population (healthy individuals) in subscale of the SF-36. The EDSS score was only predictive for physical functioning . Depression was significantly higher in those with MS than the healthy group (P