Side Effects of Transplant Immunosuppressive Therapy in Post Renal Transplant Recipients, Mazandaran, Northern Iran

Abstract

Background: Post-kidney transplant survival relies on patient adherence to the intake of immunosuppressive medication. This study was performed to investigate complications associated with immunosuppressive therapy in renal transplantation. Methods: This cross-sectional study was conducted on 188 transplanted patients in Shahid Beheshti hospital of Babol in 2013. Check list and demographic questionnaire for data collecting were used. Then the data using were analyzed in SPSS.18 software by using chi-square test. Results: A total of 188 transplanted patients, 115 (61.2%) was male and mean age was 12.9 ± 42.9 years. 181 (96.3%) of the subjects had at least one complication. The most common complication in 142 cases (75.5%) was “excessive hair growth” and after this complication “increased blood sugar” had higher frequency and 119 (63.3%) had this complication. Severe form of gingival overgrowth in women was significantly that more than men (22 (30.1), 14 (12.2), P = 0.004), and the other side effect was not significant difference between men and women or different age groups (P > 0.05) Conclusions: Finding show that nearly all transplanted recipients suffered from one complication which need to recognize, control and treatment. It suggested that period visiting for early diagnosis and education to patient was recommend.