Alteration of Lipid Parameters in Patients With Subclinical Hypothyroidism
Author | Bashir Ahmad Laway | en |
Author | Fayaz Ahmad War | en |
Author | Sonaullah Shah | en |
Author | Raiz Ahmad Misgar | en |
Author | Suman Kumar Kotwal | en |
Issued Date | 2014-07-01 | en |
Abstract | Background: Overt hypothyroidism is associated with abnormalities of lipid metabolism, but conflicting results regarding the degree of lipid changes in subclinical hypothyroidism (SCH) exist. Objectives: The aim of this study was to assess differences in lipid profile parameters between subjects with and without SCH in a north Indian population. Patients and Methods: Serum lipid parameters of 70 patients with subclinical hypothyroidism and 100 age and sex matched euthyroid controls were evaluated in a cross-sectional study. Results: Mean serum total cholesterol (TC), triglycerides (TG) and very low-density cholesterol (VLDL) were significantly higher in patients with SCH than controls (P < 0.05). Mean TC, TG and low-density cholesterol (LDL) concentrations were higher in patients with serum thyroid stimulating hormone (TSH) greater than 10 mU/L than those with serum TSH equal to or less than 10 mU/L, but this difference was not statistically significant. No association was found between serum high-density cholesterol (HDL-C) concentration and serum TSH level. Conclusions: High TC, TG and VLDL were observed in our patients with SCH. | en |
DOI | https://doi.org/10.5812/ijem.17496 | en |
Keyword | Hypothyroidism | en |
Keyword | Lipids | en |
Publisher | Brieflands | en |
Title | Alteration of Lipid Parameters in Patients With Subclinical Hypothyroidism | en |
Type | Research Article | en |
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