A single-nucleotide polymorphism of GRIN1 in heroin and methamphetamine addicts at a rehabilitation sanatorium in Markazi province, Iran
| Author | Ahmad Hamta | en |
| Author | Maryam sahraei | en |
| Issued Date | 2017-03-20 | en |
| Abstract | Introduction: Using addictive drugs can change the amount of neurotransmitters, especially dopamine and glutamate. Glutamate has been known to trigger the relapse and tendency toward addictive drugs. The glutamate receptor ionotropic NMDA type subunit 1 (GRIN1) contains the single- nucleotide polymorphism C1001G (rs11146020) and encodes N-methyl-D-aspartic acid (NDMA) receptor subunit 1 (NR1). The present study was conducted to investigate the relationship between the rs11146020 polymorphism in GRIN1 and addiction to heroin and methamphetamine. | en |
| DOI | https://doi.org/10.22110/jkums.v20i4.3207 | en |
| Keyword | Addiction | en |
| Keyword | GRIN1 | en |
| Keyword | single-nucleotide polymorphism | en |
| Keyword | T-ARMS PCR | en |
| Publisher | Brieflands | en |
| Title | A single-nucleotide polymorphism of GRIN1 in heroin and methamphetamine addicts at a rehabilitation sanatorium in Markazi province, Iran | en |
| Type | Research Article | en |
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