Utility of Early Chest Computed Tomography to Assess COVID-19 Prognosis: A Retrospective Cohort of 166 Hospitalized Patients in Southern Iran
| Author | Farideh Keshavarzi | en |
| Author | Mohammadjavad Fallahi | en |
| Author | Abdolmehdi Baghaei | en |
| Author | Seyed Hamed Jafari | en |
| Author | Mahsa Gholami | en |
| Orcid | Farideh Keshavarzi [0009-0007-6574-2450] | en |
| Orcid | Mohammadjavad Fallahi [0000-0002-8562-5637] | en |
| Orcid | Abdolmehdi Baghaei [0000-0003-1667-3739] | en |
| Orcid | Seyed Hamed Jafari [0000-0001-5364-2566] | en |
| Orcid | Mahsa Gholami [0000-0002-8610-9546] | en |
| Issued Date | 2025-03-31 | en |
| Abstract | Background: Chest computed tomography (CT)-derived findings pose clinical value in detecting high-risk COVID-19 patients. Objectives: This retrospective cohort study aimed to assess poor hospital prognosis in COVID-19 patients using on-admission chest CT findings. Methods: This study included 166 hospitalized COVID-19 patients with a confirmed diagnosis of COVID-19 from October to December 2020 in Southern Iran. Demographic variables, on-admission clinical and laboratory data, and on-admission high-resolution chest CT (HRCT) such as visual lung involvement score, distribution, area, main pattern, and related features, as well as short-term follow-up during the hospital stay, were extracted. Poor prognosis was defined as ICU admission, need for invasive mechanical ventilation, development of acute respiratory distress syndrome, or death. Results: The COVID-19 patients with poor prognosis had a significantly higher visual lung involvement score compared to those without poor prognosis (20 [IQR: 14, 23] vs. 13 [IQR: 10, 17]; P < 0.0001). The two groups were not statistically different for other HRCT findings. In a multivariable model, lung involvement score was the only statistically significant independent variable for in-patient COVID-19 poor prognosis (odds ratio: 1.197 [95% confidence interval: 1.064, 1.348]; P = 0.003). Conclusions: On-admission chest CT findings can potentially be utilized to evaluate prognosis and guide the treatment strategy of hospitalized COVID-19 patients as early as during the emergency ward stay. | en |
| DOI | https://doi.org/10.5812/semj-144932 | en |
| Keyword | COVID-19 | en |
| Keyword | SARS-CoV-2 | en |
| Keyword | Computed Tomography | en |
| Keyword | Prognosis | en |
| Keyword | Patient Outcome Assessment | en |
| Publisher | Brieflands | en |
| Title | Utility of Early Chest Computed Tomography to Assess COVID-19 Prognosis: A Retrospective Cohort of 166 Hospitalized Patients in Southern Iran | en |
| Type | Research Article | en |
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