Antibiotic Susceptibility of <i>Klebsiella pneumonia</i> Isolates from Hospitalized Patients in Three Referral Medical Centers in Isfahan, Iran
| Author | Sayed Nassereddin Mostafavi Esfahani | en |
| Author | Soodabeh Rostami | en |
| Author | Abtin Astaraki | en |
| Orcid | Sayed Nassereddin Mostafavi Esfahani [0000-0003-3657-9248] | en |
| Issued Date | 2024-07-31 | en |
| Abstract | Background: Klebsiella pneumoniae (K. pneumoniae) is a major cause of nosocomial and community-acquired infections (CAIs). Understanding the antibiotic susceptibility of this bacterium is essential for selecting the most effective antibiotic for associated infections. Objectives: We investigated the sensitivity of K. pneumonia (KP) isolates obtained from inpatients in Isfahan, Iran. Methods: Organism identification and antibiotic susceptibility testing were conducted using standard tests. Stratification was performed based on extended spectrum beta-lactamase (ESBL) production and the source of infection acquisition (community versus hospital). Results: A total of 437 KP isolates were investigated, of which 5.5% were pan drug resistant (PDR), 56.8% were extensively drug resistant (XDR), and 18% were ESBL producers. The isolates were most susceptible to colistin (100%), aminoglycosides (62.8%), and carbapenems (55%). Nosocomial isolates showed lower sensitivity to most of the examined antibiotics. Conclusions: The high prevalence of PDR and XDR KP strains in hospitalized patients is a major problem in the studied area. | en |
| DOI | https://doi.org/10.5812/zjrms-140226 | en |
| Keyword | <i>Klebsiella Pneumonia</i> | en |
| Keyword | Microbial Sensitivity | en |
| Keyword | Tests | en |
| Keyword | Drug Resistance | en |
| Keyword | Iran | en |
| Publisher | Brieflands | en |
| Title | Antibiotic Susceptibility of <i>Klebsiella pneumonia</i> Isolates from Hospitalized Patients in Three Referral Medical Centers in Isfahan, Iran | en |
| Type | Research Article | en |
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