Advantages of Buprenorphine in Comparison to Morphine in Postoperative Pain Control
| Author | M Jafari Javid | en |
| Author | M Ghanbar | en |
| Author | A Shahidi | en |
| Author | Sh Golbabaii | en |
| Author | S Atashkhoii | en |
| Author | Sh Shahrokhi | en |
| Issued Date | 2008-07-01 | en |
| Abstract | Introduction: Pre-emptive analgesia has been used widely and effectively for post operative pain relief. In this study Bupernorphine, a partial agonist of opioids has been compared to Morphine as preemptive analgesic with the aim to achieve better pain control and less post operative complications. Materials and Methods: In this randomized double blind clinical trial, 60 patients were assigned in two equal groups of study (each group=30). Bupernorphine group received 4mcg/kg IV of the drug and morphine group received 0.1mg/kgIV of the drug, 10 minutes before induction of anesthesia. The average time of the first demand for post operative analgesic, the frequencies of demands and the total amount of administered analgesics were recorded. The incidence of post operative complications such as respiratory depression and postoperative nausea and vomiting (PONV) were recorded. Results: The average time of the first demand for analgesic in Bupernorphine group (41020minutes) was significantly longer than morphine group (24025minutes), p Conclusion: Intravenous Bupernorphine before induction of anesthesia was more effective and had fewer side effects than morphine in post operative pain management. | en |
| DOI | https://doi.org/ | en |
| Keyword | Preemptive analgesia | en |
| Keyword | Bupernorphine | en |
| Keyword | Morphine PONV | en |
| Keyword | Abdominal surgery. | en |
| Publisher | Brieflands | en |
| Title | Advantages of Buprenorphine in Comparison to Morphine in Postoperative Pain Control | en |
| Type | Research Article | en |
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