Antibacterial susceptibility patterns among E.coli isolated from urinary tract infections in Ghaem University hospital, Mashhad

Abstract

Background: Urinary tract infection is one of the most common cause of the admission patients to the hospital and clinics. Because the side effects of UTI emergency treatment is very important. The aim of this study was to determine antibiotic resistance pattern of E.coli isolated from urinary tract infections in Mashhad. Materials & Methods: We studied specimens collected from patients during 1 year period. Antibacterial susceptibility test was performed by Kirby-Bauer method against 9 common antibiotics and the data were analyzed by SPSS software. Results: During this period 6024 urine samples were examined of which 1472 had positive culture. Escherichia coli with the frequency of 33% were the leading uropathogen. About 97% of isolated E.coli was resistance to Ampicillin. Resistance rate against other antibiotics was also high. Conclusion: Considering antibiotic susceptibility pattern for E.coli which is the most common uropathogen, it seems that antibiotics like Ampicillin and Co-trimoxazol should be used cautiously for treatment of E.coli UTI; instead other antibiotics like Ciprofloxacin can be recommended.