A Comparison of Chronotropic and Dromotropic Properties of Vanillic Acid and Exercise in Aged and Young Rats
| Author | Mahin Dianat |
| Author | Maryam Radan |
| Author | Mohammad Badavi |
| Author | Alireza Sarkaki |
| Issued Date | 2018-10-31 |
| Abstract | Introduction: Cardiovascular disease represents the proportion of the global burden of disease. Age is by far the most important risk factor in developing cardiovascular or heart diseases, with approximately a tripling of risk with each decade of life. The aim of this study is to compare the effects of exercise and vanillic acid (VA) on heart rate and P-R interval (cardiac health indexes) in aged and young rats.Materials and Methods: Sixty four male Sprague - Dawley rats were divided into 8 groups. Young and aged: control, VA (10 mg/kg, gavage, 10 days), exercise (1 h, at speed 17 m/min, six times per week) and exercise + VA. Lead II electrocardiogram was recorded by Bio Amp and monitored by a Power Lab system. Heart rate (as chronotropic property) and P-R interval (as dromotropic property) were calculated from ECG recording. ANOVA was used for statistical analysis and P |
| DOI | https://doi.org/ |
| Keyword | Vanillic acid |
| Keyword | Aging |
| Keyword | Exercise |
| Keyword | Chronotropic |
| Keyword | Dromotropic |
| Keyword | Rat |
| Publisher | Brieflands |
| Title | A Comparison of Chronotropic and Dromotropic Properties of Vanillic Acid and Exercise in Aged and Young Rats |
| Type | Research Article |
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