Significance of exosomes in COVID-19 pathogenesis and therapy
| Author | Parviz Basiri | en |
| Author | Mohammad Hasan Soheilifar | en |
| Author | sima nobari | en |
| Author | Amir Hasan Nikfarjam | en |
| Author | Hoda Keshmiri Neghab | en |
| Author | Saeid Afshar | en |
| Author | Shima Ghorbanifar | en |
| Author | Ali Mahdavinezhad | en |
| Orcid | Mohammad Hasan Soheilifar [0000-0002-1359-2944] | en |
| Orcid | Hoda Keshmiri Neghab [0000-0003-1895-6695] | en |
| Orcid | Saeid Afshar [0000-0001-5136-4259] | en |
| Issued Date | 2021-12-31 | en |
| Abstract | Exosomes are lipid bilayer-enclosed nano-sized vesicles, which carry various biomolecules including proteins, lipids, and microRNAs. SARS-CoV-2-loaded exosomes can be entered into the susceptible host cells, and transported viral components which are associated with viral particles intercellular transmission and spread of infection. Over-stimulation of the immune system followed by excessive proinflammatory cytokine production is a hallmark of COVID-19. Mesenchymal stem cell-derived exosomes are a potential therapeutic option in COVID-19 due to their ability to decrease cytokine storm, improve tissue regeneration, and prevent multi-organs failure. Unraveling the exact role of exosomes underlying COVID-19 infection will be beneficial in understanding novel aspects of COVID-19 pathogenesis and therapy. This study aimed to investigate the importance of exosomes in COVID-19 | en |
| DOI | https://doi.org/ | en |
| Keyword | SARS-CoV-2 | en |
| Keyword | Exosome | en |
| Keyword | COVID-19 | en |
| Keyword | Therapy | en |
| Keyword | اگزوزوم | en |
| Keyword | درمان | en |
| Publisher | Brieflands | en |
| Title | Significance of exosomes in COVID-19 pathogenesis and therapy | en |
| Type | Research Article | en |
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