The Relationship Between the Score of Adherence to the Mediterranean Diet, the Dietary Approaches to Stop Hypertension Diet, the Healthy Eating Index, and the Risk of Non-Alcoholic Fatty Liver Disease in Iranian Adults: A Case-Control Study

AuthorElham Pirabbasien
AuthorHossein Bavi Behbahanien
AuthorZahra Salimien
AuthorAnahita Mansoorien
AuthorNarges Dehghansereshten
AuthorMaryam Asadien
OrcidAnahita Mansoori [0000-0003-2935-9589]en
OrcidMaryam Asadi [0000-0002-2510-3722]en
Issued Date2023-10-28en
AbstractBackground: Evidence suggests that healthy dietary patterns such as Dietary Approaches to Stop Hypertension (DASH), Mediterranean diet (MED), and Healthy Eating Index 2015 (HEI-2015) may reduce the risk of non-alcoholic fatty liver disease (NAFLD) albeit with controversial results. Objectives: This study aimed to investigate possible associations between the NAFLD risk and adherence to the MED, DASH, and HEI-2015 diets. Methods: A case-control study was conducted involving 122 NAFLD patients and 122 non-NAFLD patients. A gastroenterologist confirmed the NAFLD diagnosis. A 147-item food frequency questionnaire (FFQ) was used to collect the dietary data, and the scores for MED, DASH diet, and HEI-2015 were obtained. Multivariable logistic regression was used to calculate the odds ratio (OR) and 95% confidence intervals (Cis). Results: The highest pentile of adherence to the DASH diet was significantly associated with the lowest risk of NAFLD (OR: 0.37, 95% CI: 0.14 - 0.92, P trend = 0.03). This association remained significant after adjustment for the confounding variable NAFLD (OR: 0.33, 95% CI: 0.11 - 0.96, P trend = 0.04). No significant difference was found between NAFLD risk and adherence to the MED and HEI-2015. Conclusions: This study demonstrated that the highest score of adherence to the DASH diet was associated with the lowest risk of NAFLD.en
DOIhttps://doi.org/10.5812/zjrms-138464en
KeywordFatty Liveren
KeywordDietary Patternen
KeywordHealthy Dieten
PublisherBrieflandsen
TitleThe Relationship Between the Score of Adherence to the Mediterranean Diet, the Dietary Approaches to Stop Hypertension Diet, the Healthy Eating Index, and the Risk of Non-Alcoholic Fatty Liver Disease in Iranian Adults: A Case-Control Studyen
TypeResearch Articleen

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