The Effect of Body Mass Index on Patient and Graft Survival Rate in Kidney Transplanted Patients in Iran
| Author | Mousa Ghelichi Ghojogh | en |
| Author | Shaker Salarilak | en |
| Author | Ali Taghezadeh Afshari | en |
| Author | Hamid Reza Khalkhali | en |
| Author | Mohammad Reza Mohammadi-Fallah | en |
| Author | Khadijeh Mkhdoomi | en |
| Issued Date | 2017-07-31 | en |
| Abstract | Background: The number of patients with overweight and obesity requiring renal transplant in the past 2 decades increased considerably. Objectives: The current study aimed at evaluating the effect of body mass index (BMI) on graft and patients survival rate. Design: In the current retrospective, cross sectional study, transplant recipients were divided into 3 groups based on their BMI: group 1 (BMI < 18.5 kg/m2), group 2 (BMI = 18.5 to 25 kg/m2), and group 3 (BMI > 25 kg/m2). Kaplan-Meier formula was used to calculate the patient survival rate, log-rank test to compare the survival curves, analysis of variance (ANOVA) to compare continuous variables, and the Chi-square test to compare the classified data. Statistical analysis was performed by SPSS version 19. P values ≤ 0.05 were considered significant. Results: The 5-year follow-up on patients’ survival rate in groups 1, 2, and 3 was 91% ± 0.03%, 91% ± 0.01%, and 80 ± 0.03%, respectively. Also, the 5-year graft survival rate in groups 1, 2, and 3 was 90% ± 0.02%, 85% ± 0.02%, and 76 ± 0.03%, respectively. There were significant differences between BMI status and gender of the recipients (P value = 0.003) and those of the donors (P value = 0.003), type of kidney in donors (P value = 0.001), type of dialysis in recipient (P value = 0.001), history of type 2 diabetes mellitus in recipient (P value = 0.001), recipient age (P value = 0.001), duration of hospitalization (P = 0.026), cholesterol levels after 1 year (P value = 0.001), and BMI status of the recipient. Conclusions: The results also indicated that the graft survival rate of the recipients was not statistically different in terms of BMI; thus, the results suggested that to allow of counting in patients included overweight and obesity kidney transplantation as appropriate action treatment. | en |
| DOI | https://doi.org/10.5812/numonthly.14386 | en |
| Keyword | Kidney Transplantation | en |
| Keyword | Graft Survival | en |
| Keyword | Body Mass Index | en |
| Publisher | Brieflands | en |
| Title | The Effect of Body Mass Index on Patient and Graft Survival Rate in Kidney Transplanted Patients in Iran | en |
| Type | Research Article | en |
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