Sodium Potassium ATPase and Glucose 6 Phosphate Dehydrogenase Activity in Patients with Hyperthyroidism: A Comparison with Euthyroid Patients

Author	A Prasad	en
Author	S Nayak	en
Issued Date	2009-01-31	en
Abstract	Background: Sodium potassium ATPase (Na+-K+ ATPase) and Glucose 6 phosphate dehydrogenase (G 6 PD) activities in different tissues have been found to be stimulated by thyroid hormones. In erythrocytes, the activities of these enzymes were reported to vary. The aim of our study was to determine the sodium potassium AT-Pase and glucose 6 phosphate dehydrogenase ac-tivities in patients with hyperthyroidism and compare them with those of patients with euthy-roid goiter. Materials and Methods: After approval from the Institutional Ethics Committee and obtaining in-formed consent from all patients, 40 hyperthyro-id patients (17 men, 23 women; mean age 44.75±2.6 years) and 50 patients with euthyroid goiter (13 men, 37 women; mean age 37.2±1.6 years) were included in the study. They were classified based on T3, T4, TSH measurements. Erythrocyte Na+-K+ ATPase and G 6 PD activity were measured using spectrophotometry. Results: In hyperthyroid patients, Na+-K+ AT-Pase activity was significantly lower compared to euthyroid controls (134.98±3.78 vs. 164.34±3.85 nmol pi/hr.mg protein, p	en
DOI	https://doi.org/	en
Keyword	Sodium potassium ATPase	en
Keyword	Glucose 6 phosphate dehydrogenase	en
Keyword	Hyperthyroidism	en
Publisher	Brieflands	en
Title	Sodium Potassium ATPase and Glucose 6 Phosphate Dehydrogenase Activity in Patients with Hyperthyroidism: A Comparison with Euthyroid Patients	en
Type	Research Article	en

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