A Mini-review on the Necessity of Expanding Personalized Medicine for the Future of Various Aspects of Pain Management

Abstract

Pain is recognized as a deeply personal, psychological, and social sensation, the perception of which is influenced by diverse factors. The intensity and nature of pain vary among individuals, rendering pain a highly personal phenomenon that warrants tailored approaches. Precision medicine is a therapeutic paradigm grounded in the evaluation of multiple patient-specific factors, including environmental factors, lifestyle, and genetic variations, to determine the most suitable treatment approach for each individual. Research indicates that certain genetic variations can influence how individuals experience and respond to pain. While there is limited evidence in leveraging genetic testing results to tailor treatment approaches, recent years have shown promising outcomes in managing surgical pain or pain associated with opioid use or cessation.