Antioxidant effect of pimpinella anisum and cinnamomum zeylanicum on cell membrane of hepatocytes, LDL, and nonenzymatic glycosylation of hemoglobin

Abstract

Background & Objectives: Free radicals especially reactive oxygen metabolites can damage DNA, proteins, enzymes, and membrane lipids. Lipid peroxidation in LDL and hepatocyte membrane may be involved in atherosclerosis and hepatic disease, respectively. nonenzymatic glycosylation of hemoglobin may be involved in complications of diabetes. Antioxidants including vitamin E may inhibit such reactions. Due to oxidant-antioxidant imbalance, free radicals may cause destructive effects. We studied the antioxidant effects of pimpinella anisum and cinnamomum zeylanicum on cell membrane of hepatocytes, LDL, and nonenzymatic glycosylation of hemoglobin.