C-Reactive Protein in Angiographically Documented Stable Coronary Disease

Abstract

Background: The association between C-reactive proteins (CRP), a marker of inflammation, and major coronary risk factors has been highlighted in several investigations. CRP is associated with acute cardiac events and can predict their occurrence. The aim of this study was to evaluate the association between CRP serum level and coronary artery disease (CAD) along with it’s major risk factors, in patients with stable angina pectoris.Patients and Methods: In a cross-sectional case control study, CRP and major coronary risk factors including cholesterol, diabetes mellitus (DM) smoking and hypertension were evaluated in 200 angiographically documented CAD (case group) and 120 subjects with normal coronary arteries(control group).Results: Of 320 subjects 50 in both case and control groups were presented with a CRP≥6 mg/dl, with 30 (60%) female and 20 (40%) male patients. There was a significant association between CRP≥6 mg/dl and those with age>60 years (P=0.002), hypertensive subjects (P