Antibiotic Resistance in <i>Staphylococcus aureus</i> in Patients Hospitalized in Imam Reza Hospital of Kermanshah, Iran (2016 - 2018)
| Author | Mohammad Hossein Zamanian | en |
| Author | Marya Shirvani | en |
| Author | Alireza Janbakhsh | en |
| Author | Babak Sayad | en |
| Author | Siavash Vaziri | en |
| Author | Zeinab Mohseni Afshar | en |
| Author | Ronak Miladi | en |
| Author | Sedigheh Khazaei | en |
| Author | Feizollah Mansouri | en |
| Author | Mandana Afsharian | en |
| Author | Mitra Tarlan | en |
| Orcid | Mohammad Hossein Zamanian [0000-0002-5459-3695] | en |
| Orcid | Marya Shirvani [0000-0003-3690-2594] | en |
| Orcid | Alireza Janbakhsh [0000-0003-0740-6823] | en |
| Orcid | Babak Sayad [0000-0001-8686-9986] | en |
| Orcid | Siavash Vaziri [0000-0002-3907-6155] | en |
| Orcid | Zeinab Mohseni Afshar [0000-0002-1085-374X] | en |
| Orcid | Ronak Miladi [0000-0002-3330-3142] | en |
| Orcid | Sedigheh Khazaei [0000-0002-3488-0849] | en |
| Orcid | Feizollah Mansouri [0000-0002-5316-3220] | en |
| Issued Date | 2021-12-31 | en |
| Abstract | Background: Staphylococcus aureus is an opportunistic pathogen, which often causes asymptomatic diseases. This bacterium could cause several disorders, ranging from skin infections to life-threatening diseases. S. aureus could also develop resistance to a wide range of antibiotics. Objectives: The present study aimed to investigate the prevalence and pattern of antibiotic resistance in isolated S. aureus in Imam Reza Hospital of Kermanshah, Iran. Methods: This descriptive cross-sectional study was conducted on 2,228 patients with a positive S. aureus culture who were admitted to Imam Reza Hospital during 2016 - 2018. In accordance with the CLSI protocol, bacterial isolates were separated using laboratory tests, and antibiotic susceptibility was assessed using the standard disk-diffusion method. Data analysis was performed in SPSS version 24. Results: Most of the S. aureus-positive cases were isolated from the emergency ward (43.7%), blood samples (40.1%), and urine samples (23.9%). The highest antibiotic resistance was observed against erythromycin, penicillin G, ofloxacin, cefoxitin, clindamycin, and piperacillin. With 93.3% and 81.8% sensitivity, vancomycin and teicoplanin were respectively the most effective antibiotics against S. aureus. Conclusions: According to the results, the prevalence of resistant S. aureus strains could be due to the long-term hospitalization of patients and the overuse of antibiotics in infection treatment. Therefore, proper monitoring and development of effective infection control methods are essential in these healthcare settings. | en |
| DOI | https://doi.org/10.5812/jkums.118807 | en |
| Keyword | Nosocomial Infection | en |
| Keyword | <i>Staphylococcus aureus</i> | en |
| Keyword | Antibiotic Resistance | en |
| Publisher | Brieflands | en |
| Title | Antibiotic Resistance in <i>Staphylococcus aureus</i> in Patients Hospitalized in Imam Reza Hospital of Kermanshah, Iran (2016 - 2018) | en |
| Type | Research Article | en |
Files
Original bundle
1 - 1 of 1
Loading...
- Name:
- jkums-25-4-118807.pdf
- Size:
- 131.58 KB
- Format:
- Adobe Portable Document Format
- Description:
- Article/s PDF