Vitamin D receptor gene BSMI polymorphisms in systemic lupus erythematosus and healthy subjects
| Author | M Abbasi | en |
| Author | Z Rezaie Yazdi | en |
| Author | J Tavakol Afshari | en |
| Author | MR Hatef | en |
| Author | M Sahebari | en |
| Author | M Yarjanli | en |
| Issued Date | 2009-06-30 | en |
| Abstract | Background: Vitamin D receptor (VDR) gene polymorphisms cause functional differences in immunomodulatory action of vitamin D. An association between VDR gene BSMI polymorphisms and systemic lupus erythematosus (SLE) has been documented. Objective: To compare the VDR gene BSMI polymorphisms in patients with SLE and healthy controls. Methods: This was a case-control study conducted in the city of Mashhad (Iran). Sixty patients with lupus from two outpatient rheumatology clinics and 45 non-relative healthy controls of the same sex were selected using the census procedure. VDR gene typing was performed based on polymerase chain reaction–restriction fragment length polymorphism (PCR-RFLP). The results were analyzed using chi square test while a p | en |
| DOI | https://doi.org/ | en |
| Keyword | Keywords: Systemic lupus erythematosus | en |
| Keyword | Polymorphisms | en |
| Keyword | Vitamin D | en |
| Keyword | BSMI gene | en |
| Keyword | polymorphism | en |
| Publisher | Brieflands | en |
| Title | Vitamin D receptor gene BSMI polymorphisms in systemic lupus erythematosus and healthy subjects | en |
| Type | Research Article | en |
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