In Vitro Cytotoxicity of Plantago australis Ethanol Extract Used as an Anti-Inflammatory for the Treatment of Oral Pathologies
| Author | Isadora Luana Flores | en |
| Author | Thiago de Oliveira Gamba | en |
| Author | Rodrigo Varella de Carvalho | en |
| Author | Rafael Guerra Lund | en |
| Author | Adriana Etges | en |
| Issued Date | 2016-02-01 | en |
| Abstract | Background: Plantago australis Lam. is a plant native to southern Brazil largely used to reduce inflammation and improve the healing process. Interestingly, though, there are no previous studies evaluating the cytotoxicity of its ethanolic extract. Objectives: The main objective is to assess in vitro the cytotoxicity of the crude ethanolic extract of P. australis at different concentrations. Materials and Methods: The MTT cytotoxicity assay was performed on a 3T3 mouse fibroblast cell line to measure the in vitro cytotoxic activity of the crude formulation. Results: In vitro analysis showed that the greater the concentration of the extract, the greater the cytotoxicity. Conclusions: The crude extract of P. australis might be cytotoxic at high concentrations as evaluated against the cell line. | en |
| DOI | https://doi.org/10.17795/jjhr-28515 | en |
| Keyword | Anti-Inflammatory | en |
| Keyword | Oral Pathology | en |
| Keyword | Cytotoxicity | en |
| Keyword | Plant Extract | en |
| Keyword | <i>Plantago australis</i> | en |
| Publisher | Brieflands | en |
| Title | In Vitro Cytotoxicity of Plantago australis Ethanol Extract Used as an Anti-Inflammatory for the Treatment of Oral Pathologies | en |
| Type | Research Article | en |