Unilateral Basal Ganglion, Thalamus, and Splenium of Corpus Callosum Lesions in Deep Cerebral Venous Thrombosis: A Case Report

Abstract

Introduction: Deep cerebral venous thrombosis primarily affects young individuals, women of reproductive age, and patients with a prothrombotic state. Unilateral thalamic lesions resulting from deep cerebral venous thrombosis are relatively unusual. We describe a rare case of unilateral basal ganglion, thalamus, and splenium of the corpus callosum lesions due to thrombus in the deep cerebral venous system. Case Presentation: A 31-year-old Asian woman presented with acute-onset headache, somnolence, and left limb weakness after a miscarriage. Subsequent investigations, including computed tomography, magnetic resonance imaging, and magnetic resonance venography, confirmed deep cerebral venous thrombosis as the underlying cause of her symptoms. Because of progressive deterioration in symptoms and consciousness, she underwent emergent endovascular treatment and anticoagulation therapy, and her symptoms subsequently resolved without complications. At the 1-year follow-up, she remained asymptomatic. Conclusions: Deep cerebral venous thrombosis can induce unilateral thalamic lesions and lesions in adjacent structures, requiring increased caution in diagnosis and invasive investigations. For patients with severe symptoms despite medical treatment, endovascular intervention may serve as a viable alternative therapeutic option.