Assessing the role of rat’s orbitofrontal cortex on sleeping time and duration
| Author | AA Vafaei | en |
| Issued Date | 2005-12-31 | en |
| Abstract | Abstract Background: Sleeping is a biological rhythm controlled by many structures and neurotransmitter systems in brain. Previous evidences suggested that Orbitofrontal Cortex (OFC) is probably involved in sleeping time and the duration. Objective: The aim of this study was to determine the role of OFC area in duration and the time of sleeping by electrical lesions. Methods: Male Wistar rats were used in this experimental study. Rats were surgically implanted bilaterally guided cannulae aimed at the OFC by stereotaxic instrument. One week after recovery, a primary assessment of sleeping duration was made by Angel behavioral method followed by lesioning of OFC using a lesion-maker (electrical electrode). Measuring the behavioral manifestations continued for time and the sleeping duration. Findings: The data found in our study was indicative of a significantly increased sleeping time (P | en |
| DOI | https://doi.org/ | en |
| Keyword | Keywords: Orbitofrontal | en |
| Keyword | Sleep | en |
| Keyword | Nervous System | en |
| Publisher | Brieflands | en |
| Title | Assessing the role of rat’s orbitofrontal cortex on sleeping time and duration | en |
| Type | Research Article | en |
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