The Effect of Preparing Dialysis Machine Using Normal Saline-Heparin on the Dialysis Adequacy of Hemodialysis Patients: A Crossover, Two-Group, and Randomized Clinical Trial
| Author | Seyed Reza Borzou | en |
| Author | Hiva Azami | en |
| Author | Mahmood Gholyaf | en |
| Author | Leili Tapak | en |
| Author | Tayebeh Nazari Doust | en |
| Orcid | Seyed Reza Borzou [0000-0002-7689-9150] | en |
| Orcid | Hiva Azami [0000-0002-6975-8093] | en |
| Orcid | Mahmood Gholyaf [0000-0003-4390-6294] | en |
| Orcid | Leili Tapak [0000-0001-9554-3099] | en |
| Orcid | Tayebeh Nazari Doust [0000-0003-4364-1425] | en |
| Issued Date | 2021-02-28 | en |
| Abstract | Background: Patients with end-stage renal disease (ESRD) need adequate dialysis. Thus, identification of the ways to enhance dialysis adequacy is very important. Objectives: The present study was conducted to examine the effect of preparing a dialysis machine using a normal saline heparin method on the dialysis adequacy of hemodialysis patients. Methods: This study was conducted in Hamadan in 2019. A total of 36 patients with hemodialysis were selected using convenience sampling who were assigned to the control and intervention groups. The hemodialysis machine was primed for one month using a routine method (control) and one month using a normal saline-heparin method (intervention). Urea reduction ratio (URR) and Kt/V indices were calculated at the beginning and end of each month in the intervention and control groups. Data were analyzed using paired and independent t-test. Results: In the normal saline-heparin group, KT/V showed a statistically significant difference before and after the treatment (P = 0.013), as well as an increase in the KT/V. The URR as the mean dialysis adequacy showed a statistically significant difference (P = 0.004) between the normal saline group and the normal saline-heparin group before and after the treatment. Moreover, URR in the normal saline-heparin group increased after the treatment. In the normal saline treatment group, KT/V and URR decreased after the treatment. In the normal saline group, URR decreased after the treatment. Conclusions: Applying the hemodialysis machine preparation with a normal saline-heparin method increased dialysis adequacy in the patients who underwent hemodialysis. | en |
| DOI | https://doi.org/10.5812/numonthly.112475 | en |
| Keyword | Dialysis Adequacy | en |
| Keyword | Hemodialysis | en |
| Keyword | Normal Saline | en |
| Keyword | Heparin | en |
| Publisher | Brieflands | en |
| Title | The Effect of Preparing Dialysis Machine Using Normal Saline-Heparin on the Dialysis Adequacy of Hemodialysis Patients: A Crossover, Two-Group, and Randomized Clinical Trial | en |
| Type | Research Article | en |
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