Androgenic Anabolic Steroid, Cocaine and Amphetamine Abuse and Adverse Cardiovascular Effects

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AuthorEfren Martinez-Quintanaen
AuthorBeatriz Saiz-Udaetaen
AuthorNatalia Marrero-Negrinen
AuthorXavier Lopez-Méridaen
AuthorFayna Rodriguez-Gonzalezen
AuthorVicente Nieto-Lagoen
Issued Date2013-10-01en
AbstractIntroduction: Anabolic-androgenic steroids (AAS), a synthetic derivate of testosterone, have become a popular drug among athletes and bodybuilders to enhance muscle mass and improve the athletic performance. Many pathological effects such as hepatic and endocrine dysfunction, behavioural changes and cardiovascular complications have been reported. Case Report: Within these ast ones, we find an increase in left ventricular muscle mass, concentric myocardial hypertrophy, left ventricular diastolic dysfunction, arterial hypertension, prothrombotic effects, changes in the concentration of cholesterol levels, particularly a reduction in HDL cholesterol concentration, myocardial infarctions in relation to endothelial dysfunction, vasospasms or thrombosis and sudden cardiac death. Discussion:: We report the case of a 32-year-old patient with a history of arterial hypertension, depressive syndrome and consumption of cocaine, amphetamines and AAS who developed severe left ventricular systolic dysfunction and myocardial hypertrophy with signs of heart failure and peripheral arterial embolism.en
DOIhttps://doi.org/10.5812/ijem.8755en
KeywordAndrogenic Anabolic Steroiden
KeywordCocaineen
KeywordAmphetamineen
KeywordCardiacen
KeywordAdverse Effectsen
KeywordAbuseen
PublisherBrieflandsen
TitleAndrogenic Anabolic Steroid, Cocaine and Amphetamine Abuse and Adverse Cardiovascular Effectsen
TypeCase Reporten

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International Journal of Endocrinology and Metabolism