Regional Versus General Anesthesia for Spinal Surgery: A Randomized Controlled Trial Comparing Clinical Outcomes
| Author | Hamid Reza Khayat Kashani | en |
| Author | Saeed Mohammad Soleymani | en |
| Author | Sohrab Salimi | en |
| Author | Ahmadreza Vahdati | en |
| Author | Pooyan Alizadeh | en |
| Author | Sohrab Sadeghi | en |
| Author | Mohsen Koosha | en |
| Author | Shirzad Azhari | en |
| Author | Hadi Esmaily | en |
| Orcid | Hamid Reza Khayat Kashani [0000-0003-3711-6763] | en |
| Orcid | Saeed Mohammad Soleymani [0000-0003-1462-3930] | en |
| Orcid | Sohrab Salimi [0000-0002-9464-2703] | en |
| Orcid | Ahmadreza Vahdati [0009-0008-5255-6082] | en |
| Orcid | Pooyan Alizadeh [0000-0002-4490-9553] | en |
| Orcid | Sohrab Sadeghi [0000-0003-3723-4321] | en |
| Orcid | Mohsen Koosha [0000-0002-1660-3178] | en |
| Orcid | Shirzad Azhari [0000-0003-2049-184X] | en |
| Orcid | Hadi Esmaily [0000-0001-6915-6028] | en |
| Issued Date | 2025-04-30 | en |
| Abstract | Background: Spinal surgery can be performed under either general anesthesia (GA) or regional anesthesia (RA). Objectives: This study compared outcomes between two groups of patients undergoing spinal neurosurgery with RA versus GA. Methods: This randomized clinical trial was conducted in the Neurosurgery Ward of Imam Hossein Hospital, Tehran, Iran, from 2021-08-23 to 2022-08-23. Of 126 patients initially enrolled for spinal surgery, 26 were excluded. The remaining 100 patients were randomized into GA (n = 49) and RA (n = 51) groups. The primary outcome was operation duration. Secondary outcomes included blood loss, pain, hospital stay, and vital signs. Results: Baseline characteristics (mean age, gender, and surgery type) were similar between groups. Operation duration and anesthesia time were significantly shorter in the RA group [80.8 ± 27.9 vs 104.1 ± 43.7 minutes (P = 0.002) and 121.0 ± 30.6 vs 148.3 ± 43.8 minutes (P < 0.001), respectively]. Bleeding, nausea, and vomiting were higher in the RA group, while muscle relaxation was greater in the GA group (P < 0.05). Acetaminophen consumption was significantly higher in the GA group (P = 0.011). Both patient and surgeon satisfaction were significantly higher with RA (P < 0.05). Hemodynamics and headache incidence were comparable between groups. Conclusions: Regional anesthesia resulted in shorter surgery times and was preferred by both patients and surgeons for spinal procedures. Additionally, RA significantly reduced the need for analgesic administration. | en |
| DOI | https://doi.org/10.5812/ans-159795 | en |
| URI | https://brieflands.com/journals/ans/articles/159795 | en |
| Keyword | Spinal Surgery | en |
| Keyword | Discectomy | en |
| Keyword | Regional Anesthesia | en |
| Keyword | General Anesthesia | en |
| Publisher | Brieflands | en |
| Title | Regional Versus General Anesthesia for Spinal Surgery: A Randomized Controlled Trial Comparing Clinical Outcomes | en |
| Type | Research Article | en |
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