Impact of Smoking on the Mortality of Hospitalized Patients With COVID-19, Iran: A Cross-sectional Study

AuthorSima Hashemipouren
Authormarayam gheraatien
AuthorMilad Badrien
AuthorNafiseh Rastgooen
AuthorAref Shokrien
AuthorSohrab Esmaeil Zadehen
AuthorKhadijeh Esmaielzadeen
OrcidNafiseh Rastgoo [0000-0003-3900-9291]en
OrcidSohrab Esmaeil Zadeh [0000-0001-5971-6503]en
Issued Date2021-09-30en
AbstractBackground: There are inconsistent data about the association of smoking with the prognosis of hospitalized patients with COVID-19. This inconsistency is so huge that some investigators have suggested some protective roles for smoking against COVID-19 disease.  Objective: This study was designed to investigate the association of smoking with mortality in hospitalized patients with COVID-19. Methods: This cross-sectional study was conducted on 493 adult patients with COVID-19 disease. Other underlying diseases, clinical and laboratory findings, and mortality rates were compared between smoking and non-smoking patients using univariate and multivariate analyses. Results:  The prevalence of current smoking among hospitalized patients was 6.1%. Clinical complaints and disease severity at admission were similar between smokers and non-smokers. Leukocyte count and blood sugar were higher in smokers compared to non-smokers (P=0.003, P=0.018, respectively). The rate of ICU admission and days of hospitalization were comparable between smokers and non-smokers. However, smokers had a significantly higher mortality rate than non-smokers (36.7% vs 13.8%, respectively, P=0.001). After adjusting for significantly different variables in univariate analysis, smoking was associated with a 3.78 times higher mortality rate (OR=3.78, 95% CI: 1.48-9.67, P=0.005). Conclusion: Smoking is an independent predictor of mortality in hospitalized patients with COVID-19.en
DOIhttps://doi.org/en
KeywordCOVID-19en
KeywordSmokingen
KeywordMortalityen
KeywordIranen
PublisherBrieflandsen
TitleImpact of Smoking on the Mortality of Hospitalized Patients With COVID-19, Iran: A Cross-sectional Studyen
TypeResearch Articleen

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