A Survey on the Fluctuations of Liver Enzymes in Severely Dehydrated Children with Acute Gastroenteritis
| Author | Iraj Shahramian | en |
| Author | Mahdi Shirdel | en |
| Author | Mojtaba Delaramnasab | en |
| Author | Alireza Sargazi | en |
| Author | Mohammad Sefatgol | en |
| Author | Ali Bazi | en |
| Orcid | Iraj Shahramian [0000-0002-4134-1405] | en |
| Orcid | Mahdi Shirdel [0000-0002-1469-1629] | en |
| Orcid | Mojtaba Delaramnasab [0000-0002-2958-3671] | en |
| Orcid | Alireza Sargazi [0000-0003-1937-6051] | en |
| Orcid | Ali Bazi [0000-0003-4872-1352] | en |
| Issued Date | 2019-07-31 | en |
| Abstract | Background: Acute gastroenteritis (AGE) is a potential life-threatening condition in young children. Objectives: Our aim was to assess hepatic enzymes levels in children with AGE and severe dehydration (> 10%). Methods: We enrolled 138 children with AGE admitted to the Amir-Al-Momenin Hospital of Zabol city in 2016. Children with severe dehydration (> 10%), according to the Vesikari score, were included. Complete blood count, selected inflammatory markers, and hepatic enzymes were investigated. Results: Males and females comprised 89 (64.5%) and 49 (35.5%) of the cases, respectively. The mean age was 3 ± 2.7 years old. Concomitant aspartate aminotransferase (AST) and alanine aminotransferase (ALT) elevation and isolated AST elevation were observed in 22 (15.9%) and 60 (43.5%) of the patients, respectively. Normal AST and ALT levels were observed in 56 (40.6%) of the patients. The AST level significantly correlated with age (r = -0.230, P = 0.007) and platelet count (r = 0.184, P =0.03). Significant correlations were also detected between ALT level and age (r = -0.230, P = 0.007), ESR (r = -0.240, P = 0.03), and K+ level (r = 0.244, P = 0.03). Conclusions: Our results highlighted relatively high frequency of elevated liver enzymes in severely dehydrated children with AGE. | en |
| DOI | https://doi.org/10.5812/gct.92181 | en |
| Keyword | Gastroenteritis | en |
| Keyword | Aspartate Aminotransferases | en |
| Keyword | Alanine Transaminase | en |
| Keyword | Liver Diseases | en |
| Publisher | Brieflands | en |
| Title | A Survey on the Fluctuations of Liver Enzymes in Severely Dehydrated Children with Acute Gastroenteritis | en |
| Type | Research Article | en |
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