Epidemiological Investigation of Iranian Patients with Pulmonary Embolism Based on Medication

Abstract

Background: The primary cause of mortality in pulmonary embolism (PE) is believed to be the lack of emergency treatment. Objectives: This study aimed to assess the outcomes of primary treatment and evaluate complications based on the type of medication used in Iranian PE patients after hospital discharge. Methods: This retrospective study was conducted on 108 PE patients admitted to Shohada Tajrish Hospital, Tehran, Iran, during 2018 - 2019. Clinical manifestations, treatment methods, drug-related complications, and prognosis were analyzed within six months post-discharge. Results: A significant association was observed between underlying diseases and the mortality rate (P < 0.05). The frequency of prescribed medications in PE patients was as follows: 60% for rivaroxaban, 9% for apixaban, 14% for warfarin, and 17.5% for enoxaparin. No significant correlation was found between death, bleeding, and the type of drug used. Conclusions: The increased mortality rate in PE patients is strongly associated with underlying conditions, such as cancer. The use of anticoagulants significantly reduces mortality rates in PE patients.