Evaluation of the Effect of ASD Closure Using the Device Method in Improving Echocardiographic and Clinical Parameters in Patients Over 40 Years of Age from 2016 to 2019
| Author | Sedigheh Saedi | en |
| Author | Nasim Nemati | en |
| Issued Date | 2025-12-31 | en |
| Abstract | Background: Atrial septal defect (ASD) is one of the most common congenital heart diseases in adults, and the treatment method involves closing these defects with intracardiac devices through angiographic or surgical techniques. So far, detailed and extensive studies on the long-term effects of these treatments, especially in older ages, have not been conducted and published. Objectives: The present study aimed to investigate the effect of ASD closure by surgical and device methods in improving echocardiographic and clinical parameters in patients over 40 years of age from 2016 to 2019 at Shahid Rajai Heart and Vascular Center. Methods: In this retrospective cohort study, the statistical population included all ASD patients over 40 years of age who visited Shahid Rajai Hospital between 2016 and 2019 and underwent ASD device closure (180 patients). To collect data, in addition to demographic information such as age, gender, clinical status, and underlying diseases, the patients' echocardiographic parameters were collected at 3 - 6 and 12 months after the procedure, which were available in their files. Chi-square and ANOVA were used to analyze the collected data. Results: The results of the present study showed that clinical symptoms improved significantly during the 3 to 6 months and 12-month follow-up in each ASD device closure group. Most echocardiographic parameters, including left ventricular ejection fraction (LVEF), left ventricular (LV) diastolic dysfunction, right ventricular (RV) function, LV size, RV size, left atrial (LA) size, right atrial (RA) size, mitral regurgitation (MR), tricuspid regurgitation (TR), and systolic pulmonary artery pressure (PAP), improved significantly during the 3 to 6 months and 12-month follow-up in the ASD device closure group. Conclusions: In general, the device method leads to improvement in clinical symptoms, although echocardiographic parameters improved more in the ASD device closure group. Therefore, in second-order ASD that meet the intrusion conditions, the choice of device closure method is preferable to open-heart surgery. | en |
| DOI | https://doi.org/10.5812/icrj-163206 | en |
| Keyword | Atrial Septum | en |
| Keyword | Echocardiography | en |
| Keyword | ASD Device Closure | en |
| Keyword | Outcome | en |
| Publisher | Brieflands | en |
| Title | Evaluation of the Effect of ASD Closure Using the Device Method in Improving Echocardiographic and Clinical Parameters in Patients Over 40 Years of Age from 2016 to 2019 | en |
| Type | Research Article | en |
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