The Effect of Interval Training on PTX3, VCAM-1, and CRP in Rats with Metabolic Syndrome
| Author | Seyed Vali Valinejad | en |
| Author | Mahnaz Omidi | en |
| Author | Abdolhossein Taheri Kalani | en |
| Orcid | Mahnaz Omidi [0000-0002-4631-7308] | en |
| Orcid | Abdolhossein Taheri Kalani [0000-0003-3668-0266] | en |
| Issued Date | 2023-03-31 | en |
| Abstract | Background: Sedentary lifestyle and lack of exercise cause cardiovascular diseases and metabolic syndrome. Decreased movement in recent decades has caused cardiovascular diseases. Methods: In this research, 35 male Wistar rats weighing 220 ± 20 g were divided into 5 groups (seven rats in each group) by a simple random method. The first and second experimental groups were given 100 grams per liter of fructose with water for 6 weeks, and the third experimental group received this for 14 weeks. The training group performed the interval training protocol on the treadmill for eight weeks and 5 days a week. One-way analysis of variance (ANOVA) was used to compare the groups. Results: The use of the fructose diet for 6 weeks and 14 weeks caused metabolic syndrome in male Wistar rats. Induction of metabolic syndrome increased the plasma levels of PTX3, VACM-1, and CRP at the end of 6 weeks (P = 0.001, P = 0.018, and P = 0.004, respectively) and the fourteenth week (P = 0.001, P = 0.001, and P = 0.001, respectively). Eight weeks of interval training significantly reduced PTX3, VACM-1, and CRP (P = 0.034, P = 0.027 and P = 0.021, respectively). Conclusions: The fructose diet caused metabolic syndrome and a significant increase in inflammatory markers in rats, and high-intensity interval training significantly reduced inflammatory factors in them. | en |
| DOI | https://doi.org/10.5812/amh-137768 | en |
| Keyword | Interval Training | en |
| Keyword | Wistar Rats | en |
| Keyword | Metabolic Syndrome | en |
| Keyword | Vascular Inflammation Indicators, Systemic Inflammation Indicators | en |
| Keyword | Fructose Diet | en |
| Publisher | Brieflands | en |
| Title | The Effect of Interval Training on PTX3, VCAM-1, and CRP in Rats with Metabolic Syndrome | en |
| Type | Research Article | en |
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