Relationship between serum vitamin D level and severity of rheumatoid arthritis
Author | mahnaz abbasi | en |
Author | SA Farzam | en |
Author | mahnaz abbasi | en |
Author | A Akbari | en |
Issued Date | 2014-02-13 | en |
Abstract | Background: Recent studies have suggested a relation between vitamin D serum level and autoimmune diseases including rheumatoid arthritis (RA). Also, vitamin D has an important role in regulating the immune system. Objective: The present study aimed at exploring the relation between serum level of vitamin D and severity of RA. Methods: The study group consisted of 153 RA patients not on vitamin D supplements who had referred to Qazvin Avicenna Hospital. Disease activity was assessed according to the disease activity score28 (DAS28). Serum levels of vitamin D and Erythrocyte Sedimentation Rate (ESR) were determined for all the participants. Findings: Vitamin D deficiency was found in 105 RA patients (68.6%). Patients were divided into three groups of low, moderate and high disease activity according to DAS28 score with 86 (56.2%), 33 (21.5%) and 34 (22.2%) patients respectively. A significant negative correlation was found between serum level of vitamin D and disease severity according to DAS28. Similarly, a negative correlation was shown to exist between the patients' pain intensity according to VAS score, and their ESR serum level (P | en |
DOI | https://doi.org/ | en |
Keyword | Rheumatoid Arthritis | en |
Keyword | Vitamin D Deficiency | en |
Keyword | Disease Severity | en |
Publisher | Brieflands | en |
Title | Relationship between serum vitamin D level and severity of rheumatoid arthritis | en |
Type | Research Article | en |
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