Effect of L-carnitine on Troponin, IL-6 and HS–CRP levels after Coronary Artery Bypass Graft Surgery
| Author | Ali Khalili | en |
| Author | Kamal Fani | en |
| Author | Mahdyieh Naziri | en |
| Author | Mahnoosh Foroughi | en |
| Author | Farzaneh Dastan | en |
| Author | Ali Dabbagh | en |
| Author | Hossein Ali Jelveh Moghaddam | en |
| Author | alireza jahangirifard | en |
| Orcid | Kamal Fani [0000-0002-7921-257X] | en |
| Orcid | Farzaneh Dastan [0000-0001-7253-4333] | en |
| Orcid | Ali Dabbagh [0000-0003-4344-8131] | en |
| Issued Date | 2019-06-30 | en |
| Abstract | Background: L-carnitine seems to be able to prevent complications after heart surgery using Cardiopulmonary bypass (CPB) and the adverse effects of pump usage. This study aimed to evaluates the effects of L-carnitine on cardiac biomarkers and operation characteristics after coronary artery bypass graft (CABG) surgery.Methods and materials: In this randomized triple-blinded, sixty patients undergoing elective CABG surgery were divided into three equal groups to receive 2gr oral L-carnitine (group A), 5gr oral L-carnitine (group B) and placebo (group C) 2 hours before surgery. IL-6, creatinine, and high sensitivity C-reactive protein (HS–CRP) levels, CK-MB, cardiac troponin and inotrope administration in ICU or after CPB were recorded for all patients at baseline levels and at 8 or 24 hours postoperatively.Results: There was an evidence of a significant difference in CPK-MB level and number of red blood cell packed used in group A was lower than group C (p | en |
| DOI | https://doi.org/10.22037/jcma.v4i2.26169 | en |
| Keyword | Coronary Artery Bypass Graft Surgery | en |
| Keyword | IL-6, HS–CRP levels | en |
| Keyword | L-carnitine | en |
| Keyword | Troponin | en |
| Publisher | Brieflands | en |
| Title | Effect of L-carnitine on Troponin, IL-6 and HS–CRP levels after Coronary Artery Bypass Graft Surgery | en |
| Type | Research Article | en |
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