A Computational Study of Some Benzenesulfonamide Derivatives as HIV- 1 Protease Enzyme Inhibitors: Three-Dimensional Quantitative Structure-Activity Relationship and Molecular Docking
| Author | Rahman Abdizade | en |
| Author | Tooba Abdizadeh | en |
| Orcid | Rahman Abdizade [0000-0002-9977-1344] | en |
| Orcid | Tooba Abdizadeh [0000-0003-2715-562X] | en |
| Issued Date | 2025-11-30 | en |
| Abstract | Background: The prevalence of human immunodeficiency virus 1 (HIV-1) infection remains a global concern due to the lack of a definitive treatment. Human immunodeficiency virus 1 protease is a homodimeric aspartic protease enzyme essential in the maturation process of HIV protein and could be a promising target for treating retrovirus infections. | en |
| DOI | https://doi.org/10.69107/koomesh-159682 | en |
| URI | https://brieflands.com/journals/koomesh/articles/159682 | en |
| Keyword | HIV-1 protease | en |
| Keyword | 3D-Quantitative Structure-Activity Relationship | en |
| Keyword | Molecular Docking Simulation | en |
| Keyword | Benzenesulfonamides | en |
| Publisher | Brieflands | en |
| Title | A Computational Study of Some Benzenesulfonamide Derivatives as HIV- 1 Protease Enzyme Inhibitors: Three-Dimensional Quantitative Structure-Activity Relationship and Molecular Docking | en |
| Type | Research Article | en |