Investigating the Role of Tumor-Associated Macrophages in the Resistance of Brain Metastatic Tumor Cells to Paclitaxel in Two- Dimensional and Three-Dimensional Cell Culture Conditions

AuthorMahnaz Siahien
AuthorMohammad Kamalabadi Farahanien
AuthorAmir Atashien
AuthorSepehr Zamanien
OrcidMohammad Kamalabadi Farahani [0000-0002-4768-2577]en
OrcidAmir Atashi [0000-0002-3889-5642]en
OrcidSepehr Zamani [0000-0001-8098-1467]en
Issued Date2025-07-31en
AbstractBackground: Brain metastasis is a devastating complication in breast cancer patients. Tumor-associated macrophages (TAMs) are cells in innate immunity, repair, and homeostasis. These cells play an important role in drug resistance in the metastatic microenvironment.en
DOIhttps://doi.org/10.69107/koomesh-149732en
KeywordTumor-Associated Macrophagesen
KeywordBrain Neoplasmsen
KeywordDrug Resistanceen
Keywordpaclitaxelen
KeywordSpheroidsen
PublisherBrieflandsen
TitleInvestigating the Role of Tumor-Associated Macrophages in the Resistance of Brain Metastatic Tumor Cells to Paclitaxel in Two- Dimensional and Three-Dimensional Cell Culture Conditionsen
TypeResearch Articleen

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