Resistin In Systemic Lupus Erythematosus: Correlation with Disease Activity and Inflammatory Markers

Simple item page
AuthorZahra Rezaieyazdien
AuthorNastaran Hashemien
AuthorZahra Mirfeizien
AuthorMaryam Sahebarien
AuthorNarges Hashemien
OrcidZahra Mirfeizi [0000-0002-2967-2404]en
Issued Date2017-02-01en
AbstractObjectives: In recent years, there is some evidence that adipokins play an important role in autoimmunity and inflammation. Resistin is the novel adipocyte-derived peptid and the aim of this study was to compare its serum values in lupus patients and controls. Methods: A cross sectional study was carried out on 73 patients with the definite diagnosis of SLE. Resistin and other proinflammatory markers were compared between patients and normal age and sex match individuals. Results: There was no significant difference in serum resistin, concentrations, between patients and healthy individuals (6.88 ± 4.53 and 6.74 ± 3.74 ng/mL respectively, P = 0.704). Statistical analysis showed a positive correlation between serum, levels of resistin with CRP and ESR (P ≤ 0.008 and P ≤ 0.037 respectively), in SLE patients. Higher serum levels of resistin in patients with proteinuria were found in comparison with normal kidney patients (P = 0.022). But there was no relationship between resistin like SLEDAI score. Conclusions: Resistin was associated with in inflammatory markers but not a notable association with markers of disease activity has been detected.en
DOIhttps://doi.org/10.17795/semj43376en
KeywordSystemic Lupus Erythematosusen
KeywordAdipokineen
KeywordResistinen
KeywordInflammationen
PublisherBrieflandsen
TitleResistin In Systemic Lupus Erythematosus: Correlation with Disease Activity and Inflammatory Markersen
TypeResearch Articleen

Files

Original bundle

Now showing 1 - 1 of 1
Thumbnail Image
Name:
20482-pdf.pdf
Size:
361.37 KB
Format:
Adobe Portable Document Format
Description:
Article/s PDF
Download

Collections

Shiraz E-Medical Journal